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The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment

Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in most types of solid tumors, and were shown to facilitate cancer progression by supporting tumor cell growth, extracellular matrix remodeling, promoting angiogenesis, and by mediating tumor-promoting inflammation...

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Опубликовано в: :Front Immunol
Главные авторы: Monteran, Lea, Erez, Neta
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688105/
https://ncbi.nlm.nih.gov/pubmed/31428105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01835
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