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The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment

Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in most types of solid tumors, and were shown to facilitate cancer progression by supporting tumor cell growth, extracellular matrix remodeling, promoting angiogenesis, and by mediating tumor-promoting inflammation...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Monteran, Lea, Erez, Neta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688105/
https://ncbi.nlm.nih.gov/pubmed/31428105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01835
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