Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models

Extracellular matrix (ECM) plays an important role in tumor development and dissemination, but few points of therapeutic intervention targeting ECM of the tumor microenvironment have been exploited to date. Recent observations suggest that the enzymatic introduction of disulfide bond cross-links int...

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Vydáno v:Oncotarget
Hlavní autoři: Feldman, Tal, Grossman-Haham, Iris, Elkis, Yoav, Vilela, Patrick, Moskovits, Neta, Barshack, Iris, Salame, Tomer M., Fass, Deborah, Ilani, Tal
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996906/
https://ncbi.nlm.nih.gov/pubmed/32064042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27438
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