Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models

Extracellular matrix (ECM) plays an important role in tumor development and dissemination, but few points of therapeutic intervention targeting ECM of the tumor microenvironment have been exploited to date. Recent observations suggest that the enzymatic introduction of disulfide bond cross-links int...

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Publicado en:Oncotarget
Autores principales: Feldman, Tal, Grossman-Haham, Iris, Elkis, Yoav, Vilela, Patrick, Moskovits, Neta, Barshack, Iris, Salame, Tomer M., Fass, Deborah, Ilani, Tal
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996906/
https://ncbi.nlm.nih.gov/pubmed/32064042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27438
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