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PTEN in Chromatin Remodeling
The tumor suppressor phosphatase and tension homolog (PTEN) is frequently mutated in human cancers, and it functions in multiple ways to safeguard cells from tumorigenesis. In the cytoplasm, PTEN antagonizes the PI3K/AKT pathway and suppresses cellular proliferation and survival. In the nucleus, PTE...
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| Published in: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996446/ https://ncbi.nlm.nih.gov/pubmed/31570373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036160 |
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