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PTEN in Chromatin Remodeling
The tumor suppressor phosphatase and tension homolog (PTEN) is frequently mutated in human cancers, and it functions in multiple ways to safeguard cells from tumorigenesis. In the cytoplasm, PTEN antagonizes the PI3K/AKT pathway and suppresses cellular proliferation and survival. In the nucleus, PTE...
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| Publicat a: | Cold Spring Harb Perspect Med |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996446/ https://ncbi.nlm.nih.gov/pubmed/31570373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036160 |
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