Wird geladen...

Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer

Loss of phosphatase and tensin homolog (PTEN) represents one hallmark of prostate cancer (PCa). However, restoration of PTEN or inhibition of the activated PI3K/AKT pathway has shown limited success, prompting us to identify obligate targets for disease intervention. We hypothesized that PTEN loss m...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Ding, Yufeng, Li, Ni, Dong, Baijun, Guo, Wangxin, Wei, Hui, Chen, Qilong, Yuan, Huairui, Han, Ying, Chang, Hanwen, Kan, Shan, Wang, Xuege, Pan, Qiang, Wu, Ping, Peng, Chao, Qiu, Tong, Li, Qintong, Gao, Dong, Xue, Wei, Qin, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355211/
https://ncbi.nlm.nih.gov/pubmed/30496141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123557
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!