The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer

Mammalian SWI/SNF enzymes are ATP-dependent remodelers of chromatin structure. These multisubunit enzymes are heterogeneous in composition; there are two catalytic ATPase subunits, BRM and BRG1, that are mutually exclusive, and additional subunits are incorporated in a combinatorial manner. Recent f...

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Gepubliceerd in:Epigenomics
Hoofdauteurs: Wu, Qiong, Lian, Jane B, Stein, Janet L, Stein, Gary S, Nickerson, Jeffrey A, Imbalzano, Anthony N
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Future Medicine Ltd 2017
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705788/
https://ncbi.nlm.nih.gov/pubmed/28521512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2017-0034
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