SWI/SNF Chromatin Remodeling Enzyme ATPases Promote Cell Proliferation in Normal Mammary Epithelial Cells

The ATPase subunits of the SWI/SNF chromatin remodeling enzymes, Brahma (BRM) and Brahma related gene 1 (BRG1), can induce cell cycle arrest in BRM and BRG1 deficient tumor cell lines, and mice heterozygous for Brg1 are predisposed to breast tumors, implicating loss of BRG1 as a mechanism for unregu...

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Detalhes bibliográficos
Main Authors: Cohet, Nathalie, Stewart, Kathleen M., Mudhasani, Rajini, Asirvatham, Ananthi J., Mallappa, Chandrashekara, Imbalzano, Karen M., Weaver, Valerie M., Imbalzano, Anthony N., Nickerson, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320666/
https://ncbi.nlm.nih.gov/pubmed/20333683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22072
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