Drysdalin, an antagonist of nicotinic acetylcholine receptors highlights the importance of functional rather than structural conservation of amino acid residues

Snake venom neurotoxins are potent antagonists of nicotinic acetylcholine receptors (nAChRs). Here, we describe a novel member of class 3c long‐chain neurotoxin drysdalin from the venom of Drysdalia coronoides. Drysdalin lacks three of the eight conserved classical functional residues critical for n...

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Sparad:
Bibliografiska uppgifter
I publikationen:FASEB Bioadv
Huvudupphovsmän: Chandna, Ritu, Tae, Han‐Shen, Seymour, Victoria A. L., Chathrath, Shifali, Adams, David J., Kini, R. Manjunatha
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996315/
https://ncbi.nlm.nih.gov/pubmed/32123825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.1027
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