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Methylpiperidinium Iodides as Novel Antagonists for α7 Nicotinic Acetylcholine Receptors

The α7 nicotinic acetylcholine receptor (nAChR) is expressed in neuronal and non-neuronal cells and is involved in several physiopathological processes, and is thus an important drug target. We have designed and synthesized novel piperidine derivatives as α7 nAChR antagonists. Thus, we describe here...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: López, Jhon J., García-Colunga, Jesús, Pérez, Edwin G., Fierro, Angélica
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048275/
https://ncbi.nlm.nih.gov/pubmed/30042682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00744
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