A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism

Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in metabolism. Here we show that a high fraction of lncRNAs, but not protein-coding mRNAs, are repressed during diet-induced obesity (DIO) and refeeding, wh...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pradas-Juni, Marta, Hansmeier, Nils R., Link, Jenny C., Schmidt, Elena, Larsen, Bjørk Ditlev, Klemm, Paul, Meola, Nicola, Topel, Hande, Loureiro, Rute, Dhaouadi, Ines, Kiefer, Christoph A., Schwarzer, Robin, Khani, Sajjad, Oliverio, Matteo, Awazawa, Motoharu, Frommolt, Peter, Heeren, Joerg, Scheja, Ludger, Heine, Markus, Dieterich, Christoph, Büning, Hildegard, Yang, Ling, Cao, Haiming, Jesus, Dario F. De, Kulkarni, Rohit N., Zevnik, Branko, Tröder, Simon E., Knippschild, Uwe, Edwards, Peter A., Lee, Richard G., Yamamoto, Masayuki, Ulitsky, Igor, Fernandez-Rebollo, Eduardo, Vallim, Thomas Q. de Aguiar, Kornfeld, Jan-Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994702/
https://ncbi.nlm.nih.gov/pubmed/32005828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14323-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados