LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves metabolic health and understanding BAT function is of interest for novel approaches to counteract obesity. The role of long noncoding RNAs (lncRNAs) in these processes remains elusive. We observed maternally expressed, i...

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Publicado no:Nat Commun
Main Authors: Schmidt, Elena, Dhaouadi, Ines, Gaziano, Isabella, Oliverio, Matteo, Klemm, Paul, Awazawa, Motoharu, Mitterer, Gerfried, Fernandez-Rebollo, Eduardo, Pradas-Juni, Marta, Wagner, Wolfgang, Hammerschmidt, Philipp, Loureiro, Rute, Kiefer, Christoph, Hansmeier, Nils R., Khani, Sajjad, Bergami, Matteo, Heine, Markus, Ntini, Evgenia, Frommolt, Peter, Zentis, Peter, Ørom, Ulf Andersson, Heeren, Jörg, Blüher, Matthias, Bilban, Martin, Kornfeld, Jan-Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127097/
https://ncbi.nlm.nih.gov/pubmed/30190464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05933-8
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