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LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves metabolic health and understanding BAT function is of interest for novel approaches to counteract obesity. The role of long noncoding RNAs (lncRNAs) in these processes remains elusive. We observed maternally expressed, i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Schmidt, Elena, Dhaouadi, Ines, Gaziano, Isabella, Oliverio, Matteo, Klemm, Paul, Awazawa, Motoharu, Mitterer, Gerfried, Fernandez-Rebollo, Eduardo, Pradas-Juni, Marta, Wagner, Wolfgang, Hammerschmidt, Philipp, Loureiro, Rute, Kiefer, Christoph, Hansmeier, Nils R., Khani, Sajjad, Bergami, Matteo, Heine, Markus, Ntini, Evgenia, Frommolt, Peter, Zentis, Peter, Ørom, Ulf Andersson, Heeren, Jörg, Blüher, Matthias, Bilban, Martin, Kornfeld, Jan-Wilhelm
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127097/
https://ncbi.nlm.nih.gov/pubmed/30190464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05933-8
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