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Pharmacological chaperones of ATP-sensitive potassium channels: mechanistic insight from cryoEM structures

ATP-sensitive potassium (K(ATP)) channels are uniquely evolved protein complexes that couple cell energy levels to cell excitability. They govern a wide range of physiological processes including hormone secretion, neuronal transmission, vascular dilation, and cardiac and neuronal preconditioning ag...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Martin, Gregory M., Sung, Min Woo, Shyng, Show-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994177/
https://ncbi.nlm.nih.gov/pubmed/31821855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.110667
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