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Role of Derlin-1 Protein in Proteostasis Regulation of ATP-sensitive Potassium Channels
ATP-sensitive potassium (K(ATP)) channels composed of sulfonylurea receptor 1 (SUR1) and Kir6.2 regulate insulin secretion by linking glucose metabolism with membrane potential. The number of K(ATP) channels in the plasma membrane affects the sensitivity of β-cells to glucose. Aberrant surface chann...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322999/ https://ncbi.nlm.nih.gov/pubmed/22311976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312223 |
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