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Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice

Flagella and cilia are evolutionarily conserved cellular organelles. Abnormal formation or motility of these organelles in humans causes several syndromic diseases termed ciliopathies. The central component of flagella and cilia is the axoneme that is composed of the ‘9+2’ microtubule arrangement, d...

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Vydáno v:PLoS Genet
Hlavní autoři: Morohoshi, Akane, Miyata, Haruhiko, Shimada, Keisuke, Nozawa, Kaori, Matsumura, Takafumi, Yanase, Ryuji, Shiba, Kogiku, Inaba, Kazuo, Ikawa, Masahito
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994161/
https://ncbi.nlm.nih.gov/pubmed/31961863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008585
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