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Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice

Flagella and cilia are evolutionarily conserved cellular organelles. Abnormal formation or motility of these organelles in humans causes several syndromic diseases termed ciliopathies. The central component of flagella and cilia is the axoneme that is composed of the ‘9+2’ microtubule arrangement, d...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Morohoshi, Akane, Miyata, Haruhiko, Shimada, Keisuke, Nozawa, Kaori, Matsumura, Takafumi, Yanase, Ryuji, Shiba, Kogiku, Inaba, Kazuo, Ikawa, Masahito
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994161/
https://ncbi.nlm.nih.gov/pubmed/31961863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008585
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