The nexin-dynein regulatory complex subunit DRC 1 is essential for motile cilia function in algae and humans

Primary ciliary dyskinesia (PCD) is characterized by dysfunction in respiratory and reproductive cilia/flagella and random determination of visceral asymmetry. Here, we identify the DRC1 subunit of the Nexin-Dynein Regulatory Complex (N-DRC), an axonemal structure critical for regulation of the dyne...

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Detalhes bibliográficos
Main Authors: Wirschell, Maureen, Olbrich, Heike, Werner, Claudius, Tritschler, Douglas, Bower, Raqual, Sale, Winfield, Loges, Niki T., Pennekamp, Petra, Lindberg, Sven, Stenram, Unne, Carlén, Birgitta, Horak, Elisabeth, Köhler, Gabriele, Nürnberg, Peter, Nürnberg, Gudrun, Porter, Mary E., Omran, Heymut
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818796/
https://ncbi.nlm.nih.gov/pubmed/23354437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2533
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