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DRC2/CCDC65 is a central hub for assembly of the nexin–dynein regulatory complex and other regulators of ciliary and flagellar motility

The nexin–dynein regulatory complex (N-DRC) plays a central role in the regulation of ciliary and flagellar motility. In most species, the N-DRC contains at least 11 subunits, but the specific function of each subunit is unknown. Mutations in three subunits (DRC1, DRC2/CCDC65, DRC4/GAS8) have been l...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Bower, Raqual, Tritschler, Douglas, Mills, Kristyn VanderWaal, Heuser, Thomas, Nicastro, Daniela, Porter, Mary E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909927/
https://ncbi.nlm.nih.gov/pubmed/29167384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0510
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