Changes in Airway Microbiome and Inflammation with Ivacaftor Treatment in Patients with Cystic Fibrosis and the G551D Mutation

Rationale: Modulation of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein improves clinical outcomes in patients with CF and specific CFTR genetic mutations. It remains unclear how improving CFTR function modifies existing airway infection and inflammation. Objectives: To...

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Vydáno v:Ann Am Thorac Soc
Hlavní autoři: Harris, J. Kirk, Wagner, Brandie D., Zemanick, Edith T., Robertson, Charles E., Stevens, Mark J., Heltshe, Sonya L., Rowe, Steven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993801/
https://ncbi.nlm.nih.gov/pubmed/31604026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201907-493OC
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