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Changes in Airway Microbiome and Inflammation with Ivacaftor Treatment in Patients with Cystic Fibrosis and the G551D Mutation

Rationale: Modulation of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein improves clinical outcomes in patients with CF and specific CFTR genetic mutations. It remains unclear how improving CFTR function modifies existing airway infection and inflammation. Objectives: To...

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Detalhes bibliográficos
Publicado no:Ann Am Thorac Soc
Main Authors: Harris, J. Kirk, Wagner, Brandie D., Zemanick, Edith T., Robertson, Charles E., Stevens, Mark J., Heltshe, Sonya L., Rowe, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993801/
https://ncbi.nlm.nih.gov/pubmed/31604026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201907-493OC
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