Changes in Airway Microbiome and Inflammation with Ivacaftor Treatment in Patients with Cystic Fibrosis and the G551D Mutation

Rationale: Modulation of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) protein improves clinical outcomes in patients with CF and specific CFTR genetic mutations. It remains unclear how improving CFTR function modifies existing airway infection and inflammation. Objectives: To...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Am Thorac Soc
Prif Awduron: Harris, J. Kirk, Wagner, Brandie D., Zemanick, Edith T., Robertson, Charles E., Stevens, Mark J., Heltshe, Sonya L., Rowe, Steven M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2020
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993801/
https://ncbi.nlm.nih.gov/pubmed/31604026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201907-493OC
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