Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135)

Synthetic cannabinoids (SCBs), designer drugs marketed as legal alternatives to marijuana, act as ligands to cannabinoid receptors; however, they have increased binding affinity and potency, resulting in toxicity symptoms such as cardiovascular incidents, seizures, and potentially death. N‐(adamanta...

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Vydáno v:Pharmacol Res Perspect
Hlavní autoři: Jones, Sabrina, Yarbrough, Azure L., Fantegrossi, William E., Prather, Paul L., Bush, John M., Radominska‐Pandya, Anna, Fujiwara, Ryoichi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993754/
https://ncbi.nlm.nih.gov/pubmed/32003945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.561
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