High-resolution mass spectrometric metabolite profiling of a novel synthetic designer drug, N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135) using cryopreserved human hepatocytes and assessment of metabolic stability with human liver microsomes

N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide (STS-135) is a new synthetic cannabinoid in herbal incense products discussed on internet drug user forums and identified in police seizures. To date, there are no STS-135 clinical or in vitro studies identifying STS-135 metabolic profile...

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Detalhes bibliográficos
Publicado no:Drug Test Anal
Main Authors: Gandhi, Adarsh S., Wohlfarth, Ariane, Zhu, Mingshe, Pang, Shaokun, Castaneto, Marisol, Scheidweiler, Karl B., Huestis, Marilyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232487/
https://ncbi.nlm.nih.gov/pubmed/24827428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dta.1662
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