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Metabolite profiling of RCS-4, a novel synthetic cannabinoid designer drug, using human hepatocyte metabolism and TOF-MS

BACKGROUND: Since 2009, scheduling legislation of synthetic cannabinoids prompted new compound emergence to circumvent legal restrictions. 2-(4-methoxyphenyl)-1-(1-pentyl-indol-3-yl)methanone (RCS-4) is a potent cannabinoid receptor agonist sold in herbal smoking blends. Absence of parent synthetic...

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Detalhes bibliográficos
Main Authors: Gandhi, Adarsh S, Zhu, Mingshe, Pang, Shaokun, Wohlfarth, Ariane, Scheidweiler, Karl B, Huestis, Marilyn A
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159359/
https://ncbi.nlm.nih.gov/pubmed/25046048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio.14.13
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