Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA

Whereas non-fluoropentylindole/indazole synthetic cannabinoids appear to be metabolized preferably at the pentyl chain though without clear preference for one specific position, their 5-fluoro analogs’ major metabolites usually are 5-hydroxypentyl and pentanoic acid metabolites. We determined metabo...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Wohlfarth, Ariane, Castaneto, Marisol S., Zhu, Mingshe, Pang, Shaokun, Scheidweiler, Karl B., Kronstrand, Robert, Huestis, Marilyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406957/
https://ncbi.nlm.nih.gov/pubmed/25721194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9721-0
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