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Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor

BACE1 is a transmembrane aspartic protease that cleaves various substrates and it is required for normal brain function. BACE1 expression is high during early development, but it is reduced in adulthood. Under conditions of stress and injury, BACE1 levels are increased; however, the underlying mecha...

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Detalhes bibliográficos
Publicado no:Mol Cell Neurosci
Main Authors: Saadipour, Khalil, Tiberi, Alexia, Lomardo, Sylvia, Grajales, Elena, Montroull, Laura, Mañucat-Tan, Noralyn B., LaFrancois, John, Cammer, Michael, Mathews, Paul M., Scharfman, Helen E., Liao, Francesca-Fang, Friedman, Wilma J., Zhou, Xin-Fu, Tesco, Giueseppina, Chao, Moses V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993608/
https://ncbi.nlm.nih.gov/pubmed/31422108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2019.103395
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