Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model

p75 neurotrophin receptor (p75(NTR)) has been implicated in Alzheimer’s disease (AD). However, whether p75(NTR) is involved in Tau hyperphosphorylation, one of the pathologies observed in AD, remains unclear. In our previous study, the extracellular domain of p75(NTR) blocked amyloid beta (Aβ) toxic...

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Mañucat-Tan, Noralyn B., Shen, Lin-Lin, Bobrovskaya, Larisa, Al-hawwas, Mohammed, Zhou, Fiona H., Wang, Yan-Jiang, Zhou, Xin-Fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756909/
https://ncbi.nlm.nih.gov/pubmed/31479419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102202
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