Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model

p75 neurotrophin receptor (p75(NTR)) has been implicated in Alzheimer’s disease (AD). However, whether p75(NTR) is involved in Tau hyperphosphorylation, one of the pathologies observed in AD, remains unclear. In our previous study, the extracellular domain of p75(NTR) blocked amyloid beta (Aβ) toxic...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Mañucat-Tan, Noralyn B., Shen, Lin-Lin, Bobrovskaya, Larisa, Al-hawwas, Mohammed, Zhou, Fiona H., Wang, Yan-Jiang, Zhou, Xin-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756909/
https://ncbi.nlm.nih.gov/pubmed/31479419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102202
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