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A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products
BACKGROUND: Melanoma is one of the most aggressive tumors with the remarkable characteristic of resistance to traditional chemotherapy and radiotherapy. Although targeted therapy and immunotherapy benefit advanced melanoma patient treatment, BRAFi (BRAF inhibitor) resistance and the lower response r...
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| Publicado no: | Cancer Cell Int |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6993520/ https://ncbi.nlm.nih.gov/pubmed/32021565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-1114-5 |
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