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A novel chalcone derivative suppresses melanoma cell growth through targeting Fyn/Stat3 pathway

BACKGROUND: Fyn has been documented to have oncogenic features in multiple tumors, which might be a potential therapeutic target, however, few studies on the function role of Fyn and its specific inhibitors in melanoma. METHODS: We investigated the impacts of Fyn and its inhibitor Lj-1-60 on melanom...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Tang, Ling, Long, Jing, Li, Keke, Zhang, Xu, Chen, Xiang, Peng, Cong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302361/
https://ncbi.nlm.nih.gov/pubmed/32565740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01336-2
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