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Structural Antitumoral Activity Relationships of Synthetic Chalcones

Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2’-hydroxychalcones resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated reactivity...

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Détails bibliographiques
Auteurs principaux: Echeverria, Cesar, Santibañez, Juan Francisco, Donoso-Tauda, Oscar, Escobar, Carlos A., Ramirez-Tagle, Rodrigo
Format: Artigo
Langue:Inglês
Publié: Molecular Diversity Preservation International (MDPI) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662465/
https://ncbi.nlm.nih.gov/pubmed/19333443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10010221
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