The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of (89)Zr-DFO-Pertuzumab

Rationale: The overwhelming majority of radioimmunoconjugates are produced via random conjugation methods predicated on attaching bifunctional chelators to the lysines of antibodies. However, this approach inevitably produces poorly defined and heterogeneous immunoconjugates because antibodies have...

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Detaylı Bibliyografya
Yayımlandı:Theranostics
Asıl Yazarlar: Vivier, Delphine, Fung, Kimberly, Rodriguez, Cindy, Adumeau, Pierre, Ulaner, Gary A., Lewis, Jason S., Sharma, Sai Kiran, Zeglis, Brian M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2020
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993239/
https://ncbi.nlm.nih.gov/pubmed/32042334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.39089
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