The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of (89)Zr-DFO-Pertuzumab

Rationale: The overwhelming majority of radioimmunoconjugates are produced via random conjugation methods predicated on attaching bifunctional chelators to the lysines of antibodies. However, this approach inevitably produces poorly defined and heterogeneous immunoconjugates because antibodies have...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Vivier, Delphine, Fung, Kimberly, Rodriguez, Cindy, Adumeau, Pierre, Ulaner, Gary A., Lewis, Jason S., Sharma, Sai Kiran, Zeglis, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993239/
https://ncbi.nlm.nih.gov/pubmed/32042334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.39089
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