The Influence of Glycans-Specific Bioconjugation on the FcγRI Binding and In vivo Performance of (89)Zr-DFO-Pertuzumab

Rationale: The overwhelming majority of radioimmunoconjugates are produced via random conjugation methods predicated on attaching bifunctional chelators to the lysines of antibodies. However, this approach inevitably produces poorly defined and heterogeneous immunoconjugates because antibodies have...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Vivier, Delphine, Fung, Kimberly, Rodriguez, Cindy, Adumeau, Pierre, Ulaner, Gary A., Lewis, Jason S., Sharma, Sai Kiran, Zeglis, Brian M.
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2020
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993239/
https://ncbi.nlm.nih.gov/pubmed/32042334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.39089
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