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Direct comparison of the in vitro and in vivo stability of DFO, DFO* and DFOcyclo* for (89)Zr-immunoPET
PURPOSE: Currently, the most commonly used chelator for labelling antibodies with (89)Zr for immunoPET is desferrioxamine B (DFO). However, preclinical studies have shown that the limited in vivo stability of the (89)Zr-DFO complex results in release of (89)Zr, which accumulates in mineral bone. Her...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Eur J Nucl Med Mol Imaging |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer Berlin Heidelberg
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647232/ https://ncbi.nlm.nih.gov/pubmed/31161258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-019-04343-2 |
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