Loading...
Removal of Fc Glycans from [(89)Zr]Zr-DFO-Anti-CD8 Prevents Peripheral Depletion of CD8(+) T Cells
The N-linked biantennary glycans on the heavy chain of immunoglobulin G (IgG) antibodies (mAbs) are instrumental in the recognition of the Fc region by Fc-gamma receptors (FcγR). In the case of full-length mAb-based imaging tracers targeting immune cell populations, these Fc:FcγR interactions can po...
Na minha lista:
| Udgivet i: | Mol Pharm |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307332/ https://ncbi.nlm.nih.gov/pubmed/32330387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00270 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|