The Impact of Surgery in IDH 1 Wild Type Glioblastoma in Relation With the MGMT Deregulation

Object: The treatment of choice in glioblastoma (GBM) is the maximal surgical extent of resection (EOR) followed by adjuvant chemo-radiotherapy. Furthermore, methylguanine-DNA methyltransferase (MGMT) promoter methylation is associated with prolonged overall survival (OS) and progression free surviv...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Marchi, Francesco, Sahnane, Nora, Cerutti, Roberta, Cipriani, Debora, Barizzi, Jessica, Stefanini, Federico Mattia, Epistolio, Samantha, Cerati, Michele, Balbi, Sergio, Mazzucchelli, Luca, Sessa, Fausto, Pesce, Gianfranco Angelo, Reinert, Michael, Frattini, Milo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992596/
https://ncbi.nlm.nih.gov/pubmed/32039032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01569
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