Functional and clinical significance of ROR1 in lung adenocarcinoma

BACKGROUND: Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is normally detectable in embryonic tissues and absent in adult tissues. ROR1 was shown to inhibit apoptosis, potentiate EGFR signaling and reported to be overexpressed and associated with poor prognosis in several tumor models. This...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Giovanna, Schiavone, Samantha, Epistolio, Vittoria, Martin, Francesca, Molinari, Jessica, Barizzi, Luca, Mazzucchelli, Milo, Frattini, Luciano, Wannesson
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653802/
https://ncbi.nlm.nih.gov/pubmed/33172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07587-6
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