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Functions and Regulation of the PTEN Gene in Colorectal Cancer
Phosphatase and TENsin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor gene located at chromosome 10q23.31, encoding for a 403-amino acid protein that possesses both lipid and protein phosphatase activities. The main function of PTEN is to block the PI3K pathway by dephosphorylating ph...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893597/ https://ncbi.nlm.nih.gov/pubmed/24475377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00326 |
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