Functional and clinical significance of ROR1 in lung adenocarcinoma

BACKGROUND: Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is normally detectable in embryonic tissues and absent in adult tissues. ROR1 was shown to inhibit apoptosis, potentiate EGFR signaling and reported to be overexpressed and associated with poor prognosis in several tumor models. This...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Giovanna, Schiavone, Samantha, Epistolio, Vittoria, Martin, Francesca, Molinari, Jessica, Barizzi, Luca, Mazzucchelli, Milo, Frattini, Luciano, Wannesson
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653802/
https://ncbi.nlm.nih.gov/pubmed/33172431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07587-6
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