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CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers

CRISPR-Cas immune systems in bacteria and archaea record prior infections as spacers within each system’s CRISPR arrays. Spacers are normally derived from invasive genetic material and direct the immune system to complementary targets as part of future infections. However, not all spacers appear to...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Wimmer, Franziska, Beisel, Chase L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990116/
https://ncbi.nlm.nih.gov/pubmed/32038537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03078
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