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Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems in bacteria and archaea employ CRISPR RNAs to specifically recognize the complementary DNA of foreign invaders, leading to sequence-specific cleavage or degradation of the target DNA. Recent work has s...

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Detalhes bibliográficos
Main Authors: Gomaa, Ahmed A., Klumpe, Heidi E., Luo, Michelle L., Selle, Kurt, Barrangou, Rodolphe, Beisel, Chase L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903277/
https://ncbi.nlm.nih.gov/pubmed/24473129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00928-13
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