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Diversity of CRISPR-Cas immune systems and molecular machines
Bacterial adaptive immunity hinges on CRISPR-Cas systems that provide DNA-encoded, RNA-mediated targeting of exogenous nucleic acids. A plethora of CRISPR molecular machines occur broadly in prokaryotic genomes, with a diversity of Cas nucleases that can be repurposed for various applications.
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| Publicado no: | Genome Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4638107/ https://ncbi.nlm.nih.gov/pubmed/26549499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0816-9 |
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