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Fentanyl depression of respiration: Comparison with heroin and morphine

BACKGROUND AND PURPOSE: Fentanyl overdose deaths have reached “epidemic” levels in North America. Death in opioid overdose invariably results from respiratory depression. In the present work, we have characterized how fentanyl depresses respiration, and by comparing fentanyl with heroin and morphine...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Hill, Rob, Santhakumar, Rakulan, Dewey, William, Kelly, Eamonn, Henderson, Graeme
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989952/
https://ncbi.nlm.nih.gov/pubmed/31499594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14860
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