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Fentanyl depression of respiration: Comparison with heroin and morphine

BACKGROUND AND PURPOSE: Fentanyl overdose deaths have reached “epidemic” levels in North America. Death in opioid overdose invariably results from respiratory depression. In the present work, we have characterized how fentanyl depresses respiration, and by comparing fentanyl with heroin and morphine...

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Pubblicato in:Br J Pharmacol
Autori principali: Hill, Rob, Santhakumar, Rakulan, Dewey, William, Kelly, Eamonn, Henderson, Graeme
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989952/
https://ncbi.nlm.nih.gov/pubmed/31499594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14860
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