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Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. Epidermal growth factor receptor (EGFR) has been shown to be over-expressed in TNBC and represents a rational treatment target. METHODS: We examined single agent and combinati...

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Pubblicato in:Ther Adv Med Oncol
Autori principali: Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987485/
https://ncbi.nlm.nih.gov/pubmed/32064003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919897546
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