Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. Epidermal growth factor receptor (EGFR) has been shown to be over-expressed in TNBC and represents a rational treatment target. METHODS: We examined single agent and combinati...

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Veröffentlicht in:Ther Adv Med Oncol
Hauptverfasser: Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2020
Schlagworte:
TNBC in 2019: Promising Signals for the Treatment of a Formidable Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987485/
https://ncbi.nlm.nih.gov/pubmed/32064003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919897546
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