Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. Epidermal growth factor receptor (EGFR) has been shown to be over-expressed in TNBC and represents a rational treatment target. METHODS: We examined single agent and combinati...

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發表在:Ther Adv Med Oncol
Main Authors: Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
格式: Artigo
語言:Inglês
出版: SAGE Publications 2020
主題:
TNBC in 2019: Promising Signals for the Treatment of a Formidable Disease
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987485/
https://ncbi.nlm.nih.gov/pubmed/32064003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919897546
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