Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. Epidermal growth factor receptor (EGFR) has been shown to be over-expressed in TNBC and represents a rational treatment target. METHODS: We examined single agent and combinati...

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Vydáno v:Ther Adv Med Oncol
Hlavní autoři: Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2020
Témata:
TNBC in 2019: Promising Signals for the Treatment of a Formidable Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987485/
https://ncbi.nlm.nih.gov/pubmed/32064003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835919897546
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