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Targeted treatment of advanced and metastaticbreast cancer with lapatinib

Improved molecular understanding of breast cancer in recent years has led to the discovery of important drug targets such as HER-2 and EGFR. Lapatinib is a potent dual inhibitor of HER-2 and EGFR. Preclinical and phase I studies have shown activity with lapatinib in a number of cancers, including br...

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Bibliografski detalji
Glavni autori: Corkery, Brendan, O’Donovan, Norma, Crown, John
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994213/
https://ncbi.nlm.nih.gov/pubmed/21127749
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