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The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?
The ADAMs are transmembrane proteins implicated in proteolysis and cell adhesion. Forty gene members of the family have been identified, of which 21 are believed to be functional in humans. As proteases, their main substrates are the ectodomains of other transmembrane proteins. These substrates incl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170276/ https://ncbi.nlm.nih.gov/pubmed/21906355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1559-0275-8-9 |
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