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The ADAMs family of proteases as targets for the treatment of cancer

The ADAMs (a disintegrin and metalloproteases) are transmembrane multidomain proteins implicated in multiple biological processes including proteolysis, cell adhesion, cell fusion, cell proliferation and cell migration. Of these varied activities, the best studied is their role in proteolysis. Howev...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Mullooly, Maeve, McGowan, Patricia M., Crown, John, Duffy, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004698/
https://ncbi.nlm.nih.gov/pubmed/27115328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1177684
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