Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway

Cancer cells are characterized by malignant proliferation and aberrant metabolism and are thereby liable to the depletion of nutrients and accumulation of metabolic waste. To maintain cellular homeostasis, cancer cells are prone to upregulating the canonical autophagy pathway. Here, we identified pa...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Wang, Kun, Gong, Qing, Zhan, Yujuan, Chen, Bonan, Yin, Ting, Lu, Yuhua, Zhang, Yilin, Wang, Huiqi, Ke, Junzi, Du, Biaoyan, Liu, Xiaodong, Xiao, Jianyong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987457/
https://ncbi.nlm.nih.gov/pubmed/32039209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00397
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