Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria

Cancer cells have developed chemoresistance and have improved their survival through the upregulation of autophagic mechanisms that protect mitochondrial function. Here, we report that the traditional Chinese anticancer agent tubeimoside I (Tub), which is a potent inhibitor of autophagy, can promote...

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Publicado en:Cell Death Dis
Autores principales: Wang, Kun, Zhan, Yujuan, Chen, Bonan, Lu, Yuhua, Yin, Ting, Zhou, Shikun, Zhang, Weibin, Liu, Xiaodong, Du, Biaoyan, Wei, Xianli, Xiao, Jianyong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449972/
https://ncbi.nlm.nih.gov/pubmed/32848130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02915-x
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