Tubeimoside I-induced lung cancer cell death and the underlying crosstalk between lysosomes and mitochondria

Cancer cells have developed chemoresistance and have improved their survival through the upregulation of autophagic mechanisms that protect mitochondrial function. Here, we report that the traditional Chinese anticancer agent tubeimoside I (Tub), which is a potent inhibitor of autophagy, can promote...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Kun, Zhan, Yujuan, Chen, Bonan, Lu, Yuhua, Yin, Ting, Zhou, Shikun, Zhang, Weibin, Liu, Xiaodong, Du, Biaoyan, Wei, Xianli, Xiao, Jianyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449972/
https://ncbi.nlm.nih.gov/pubmed/32848130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02915-x
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